Africa

Mpox Vaccine Study To Begin In DRC Amid Outbreak

Published

3 weeks ago

September 14, 2025

A new study is set to begin in the Democratic Republic of Congo (DRC) to assess the efficacy of the LC16m8 Mpox vaccine in African populations.

The launch comes as the country battles a major outbreak of the virus, which remains a continental public health emergency.

Health experts say the ongoing vaccination campaign in DRC offers a rare chance to gather real-world evidence about the vaccine’s performance. The study will look at how effective the vaccine is at preventing Mpox, including among children.

The Coalition for Epidemic Preparedness Innovations (CEPI) is funding the project with up to 10.4 million US dollars, a statement issued on September 11, 2025, said. The International Vaccine Institute (IVI) will serve as the study sponsor, while the Institut National pour la Recherche Biomédicale (INRB) in the DRC will co-sponsor and also lead the research and the Japan Institute for Health Security (JIHS) will act as a co-investigator.

The study is supported by the DRC Ministry of Health and the Institut National de Santé Publique (INSP) and is expected to begin this Autumn once regulatory and ethics approvals are completed.

Researchers will monitor vaccinated people in hotspot health zones in Équateur Province. They will track how many still get infected and also collect safety data from a subset of participants.

The findings are expected to guide vaccination strategies in the DRC and other Mpox-endemic regions. They could also help decide which age groups should be prioritized for vaccination.

Japan has donated three million doses of LC16m8 to DRC to protect at-risk populations. The vaccine, developed by KM Biologics, has been licensed in Japan for decades as a smallpox vaccine. It is safe and effective, including in people with well-controlled HIV.

The DRC Health Minister, Samuel Roger Kamba, said the country will be the first in Africa to collect real-world field data on the vaccine.

“The epidemiological data on Mpox have enabled us to support the response with vaccination of the populations. With this collaborative research, the DRC will be the first African country to collect essential field data on the use of the LC16m8 vaccine against Mpox.”

Dr. Manabu Sumi of Japan’s Health Ministry said LC16m8 is the only Mpox vaccine currently approved for children and could protect people of all ages.

“Building on the findings of this trial and Japan’s accumulated experience, the Ministry looks forward to working with international partners to further enhance LC16m8’s contribution to global preparedness and response efforts against Mpox.”

Africa CDC Director-General, Dr. Jean Kaseya, described the study as “a vital step in protecting Africa’s most vulnerable, especially children.”

“By turning science into action, we are building the evidence needed to guide vaccination and strengthen health security across the continent.”

Other partners, including INRB and JIHS, stressed that the project will also strengthen Africa’s ability to respond to future health emergencies.

Director-General of INRB and Principal Investigator, Prof. Jean-Jacques Muyembe, said scientific collaboration is key.

“The results generated by this study will serve as an effective guide for future Mpox outbreaks,” he said.

Dr. Norio Ohmagari of JIHS said the trial will provide rigorous real-world evidence, while Dr. Mugen Ujiie of the same institute highlighted Japan’s commitment to protecting communities from Mpox.

“The findings will help inform equitable and effective vaccination strategies across affected regions,” Dr Ujiie said.

The International Vaccine Institute’s Deputy Director General, Dr. Florian Marks, added that the study will also help build local research capacity.

“In close partnership with INRB, JIHS, CEPI, and local health teams, we are also working to strengthen local research capacity so that communities are better equipped to respond to future health emergencies,” he said.

General Director of INSP, Dr. Dieudonné Mwamba, said vaccination remains a key pillar in responding to epidemics.

Mpox, formerly known as monkeypox, causes fever, headache, muscle aches, swollen lymph nodes and skin rashes with blisters. The disease can be deadly in severe cases.

WHO and Africa CDC declared the ongoing outbreak a global and continental emergency in August 2024. As of September 2025, Mpox remains a continental health emergency in Africa.

myjoyonline.com

Related Topics:DR Congo MPox MPox Vaccine

Up Next

US Vaccine Panel Withdraws Recommendation Of Covid-19 Jab For Adults

Don't Miss

US Judge Questions Deportation Of West African Migrants To Ghana

Click to comment

International

Burkina Faso Abolishes Visa Fees for African Nationals

Published

3 weeks ago

September 13, 2025

AladdynKing

Burkina Faso has declared that all African nationals will no longer need to pay a visa fee, marking a significant step toward regional integration. Visa payments will no longer be necessary for nationals of any African nation visiting Burkina Faso, as of right now.

The Minister of Foreign Affairs, Regional Cooperation, and Burkinabe Abroad for Burkina Faso, Mahmadou Sana, made the announcement and said:

“From now on, any citizen from an African country wishing to go to Burkina Faso will not pay any amount to cover visa fees.”

The goal of this resolution is to improve cultural, diplomatic, and economic relations within the African continent. Burkina Faso wants to promote travel, trade, and cross-border cooperation by lowering financial barriers.

Additionally, the action supports Agenda 2063 of the African Union, which aims to encourage the free flow of people, products, and services around the continent. Businesses and travel companies have embraced the news, expecting more reservations and business prospects.

All things considered, the ruling presents Burkina Faso as a friendly and forward-thinking country dedicated to regional unification and promoting intra-African trade and travel.

News

Flood Alert: Bagre Dam To Spill Two Days Earlier Than Scheduled

Published

1 month ago

August 24, 2025

AladdynKing

Contrary to an earlier announcement that the spillage of the Bagre Dam would take place on Wednesday, August 27, 2025, authorities in Burkina Faso have rescheduled the exercise to Monday, August 25, 2025.

The decision follows a rapid rise in water levels that has exceeded initial projections.

In a statement, SONABEL, the agency managing the Bagre and Kompienga dams, explained that the speed of the water rise had surpassed their estimates, forcing them to open the floodgates earlier than planned.

As of Saturday, August 23, 2025, the Bagre Dam recorded an elevation of 234.27 metres with a filling rate of 90.24 per cent, just 0.73 metres below its maximum retention level.

Similarly, the Kompienga Dam stood at 177.90 metres with a filling rate of 79.36 per cent, leaving only 2.10 metres before reaching its normal retention capacity.

SONABEL stated:

🚨 Early Opening of Bagré Dam Valves 🚨
“SONABEL informs the coastal populations of the hydroelectric dam of Bagré that, following the heavy rainfall recorded in recent days, the water level of the hold has reached a critical threshold and requires a faster evacuation of the surplus.

“Consequently, SONABEL will open the valves of the dam flood evacuator from Monday, August 25, 2025 from 08 o’clock, instead of Wednesday, August 27, as initially announced.

“SONABEL therefore invites the coastal populations living downstream of the dam to remain vigilant and to take all necessary precautions against the risks of flooding that may result from this measure.

“SONABEL, together at the service of a great ambition!”

The announcement serves as an early warning to communities along the White Volta Basin in both Burkina Faso and Northern Ghana, which often experience flooding following spillage from the Bagré Dam.

graphic.com.gh

International

Mali Charges Ex‑Prime Minister With Undermining The State Over Post On X

Published

2 months ago

August 2, 2025

AladdynKing

A former prime minister of Mali, which is now under military rule, has been charged with undermining the credibility of the state over comments on social media.

After a prison visit to see detained opposition figures in July, Moussa Mara declared on X his “unwavering solidarity with prisoners of conscience”.

Mara, who served as prime minister for nine months a decade ago, has been a recent outspoken critic of the military government.

On Thursday, Mara was detained and questioned for a second time by the national cybercrime unit about his 4 July X post.

In the post, the ex-prime minister said his regular visits to see those detained were to make sure that “the flame of hope never fades in them”.

“As long as the night lasts, the sun will inevitably rise! And we will fight by all means to make that happen, and as soon as possible!” he added.

The prosecutor at the cybercrime unit said that talking about “prisoners of conscience” and saying he wanted to fight for them constituted an offence, Radio France Internationale reports.

On Friday, along with the accusation of undermining the credibility of the state, he was also charged with opposing legitimate authority and inciting public disorder.

He is due to stand trial on 29 September.

A month ago, military leader Gen Assimi Goïta was granted a five-year presidential term by the transitional parliament, which is renewable without elections.

The 41-year-old, who seized power twice, was named transitional president after the 2021 coup.

At the time he promised to hold elections the following year – but has since reneged, in a blow to efforts to restore multi-party rule in the West African state.

The junta, in power since coups in 2020 and 2021, dissolved all political parties in May following rare anti-government protests.

bbc.com